WebMay 21, 2024 · FOXO3a is a member of the FOXO transcription factor family, which plays a pivotal role in maintaining redox balance. Activation of the SIRT1/FOXO3a pathway can inhibit oxidative stress primarily by regulating antioxidant enzymes [ [13], [14], [15] ]. WebJan 15, 2024 · The 14-3-3 proteins bind to the phosphorylated FoxO3a at Thr32 and Ser253. Binding of 14-3-3 proteins to FoxO3a prevents the cytoplasmic pool of FoxO3a …
A型核纤层蛋白编码基因LMNA调控IOP1表达机制的初步研究*
WebFOXO3a were positively correlated, and both were associated with longer sur-vival in lung cancer patients. Conclusion: Overall, the present study is the first to show that Adjudin syner-gizes with paclitaxel and inhibits cell growth and metastasis by regulating the SIRT3–FOXO3a axis in SCLC; thus, Adjudin has great potential to be an anti- Web56484 Ensembl ENSG00000118689 ENSMUSG00000048756 UniProt O43524 Q9WVH4 RefSeq (mRNA) NM_001455 NM_201559 NM_019740 NM_001376967 RefSeq (protein) NP_001446 NP_963853 NP_062714 NP_001363896 Location (UCSC) Chr 6: 108.56 – 108.68 Mb Chr 10: 42.06 – 42.15 Mb PubMed search Wikidata View/Edit Human … describe diamagnetism and some examples of it
FoxO3a (75D8) Rabbit mAb Cell Signaling Technology
WebNov 15, 2016 · Besides, FoxO3a can trigger apoptosis by promoting the expressions of death receptor ligands in the extrinsic apoptotic pathway, such as Fas ligand 33 and tumor-necrosis-factor-related apoptosis ... WebDirections for Use: CST recommends transfection with 100 nM FoxO3a siRNA I 48 to 72 hours prior to cell lysis. For transfection procedure, follow protocol provided by the transfection reagent manufacturer. Please feel free to … WebJan 1, 2012 · Doxorubicn treatment induces p38 MAPK activity and FOXO3a nuclear accumulation in MCF-7 breast carcinoma cell line. A, MCF-7 cells were treated with 1 μmol/liter of doxorubicin for 0, 1, 2, 4, 8, 16, and 24 h. At the indicated time, the cells were collected and analyzed by Western blotting using the antibodies indicated. chrysler plymouth mi