Daptomycin dosing for obese patients
WebIn obese patients treated with high dose daptomycin, ... A fixed dose in obese patients of 750 mg (ABW 90–99.9 kg) or 1,000 mg (ABW≥100 kg; maximum dose) was … WebJan 30, 2024 · Food and Drug Administration-approved daptomycin dosing uses actual body weight, despite limited dosing information for obese patients. Studies report …
Daptomycin dosing for obese patients
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Web*Daptomycin IV Dose based on TBW. Consider adjusted BW if morbidly obese & using 8-12 mg/kg. Round to nearest 50 mg. ... Ertapenem IV Consider meropenem for obese patients (>100kg) WITH severe deep-seated infection . SHC Antimicrobial Dosing Guidelines in Adults These are general dosing guidelines. Doses may vary based on …
WebDec 14, 2024 · The European Medicines Agency (EMA) and FDA approved the use of daptomycin for the treatment of pediatric patients with cSSTIs at dosages of 5, 7, 9, and 10 mg/kg every 24 h for patients aged 12–17, 7–11, 2–6, and 1–2 years, respectively [ 48, 49 ], and at dosages of 7, 9, and 12 mg/kg every 24 h for patients aged 12–17, 7–11, … WebWeight-Based Dosing Recommendations for Intravenous Antimicrobials in Obese Adult Patients. Voriconazole. Daptomycin. IV Ganciclovir. IV Acyclovir. Liposomal …
WebApr 3, 2024 · Results: The adult dosing regimens of 6 mg/kg q24h or q48h daptomycin and 300-600 mg q12h ceftaroline fosamil by RI categories achieved ≥90% joint PTA when the minimum inhibitory concentrations (MICs) in the combination are at or below 1 and 4 μg/mL against MRSA. Web2. In adult patients, cefazolin (2 g if <120 kg, 3 g if ≥120 kg) and vancomycin (1 g if <80 kg, 1.5 g if ≥80 kg) dosing is based on weight. Adult patients <50 kg should refer to Patients <50 kg (Adult and Pediatric) Dosing recommendations for dosing. Weight-based dosing is recommended for all antibiotics in patients <50 kg. 3.
WebDaptomycin Dosing and Use Guidelines Dosing: Soft tissue infection = 4 mg/kg every 24 hours Staphylococcus aureus bacteremia, other deep-seated infections = 6 mg/kg …
WebCurrent medications include daptomycin 600 mg intravenous (IV) daily (6 mg/kg/Q24 hour), rifampin 300 mg per oral (PO) twice daily, aspirin, lisinopril, pantoprazole, tamsulosin, and PO hydrocortisone, levothyroxine, and subcutaneous heparin. north mpls food shelvesWebDaptomycin pharmacokinetics were studied in adult volunteers who were moderately obese (body mass index [BMI] = 25–39.9 kg/m2) or morbidly obese (BMI 40 kg/m2) and a matched (gender, age, renal function) nonobese (BMI between 18.5 … north moving companyWebIssues such as dosing strategies in obese patients, safety profiles in daily dosages exceeding 3 g, continuous infusion strategies, and renal failure are some examples where insufficient data precluded adequate coverage. ... This has been demonstrated for vancomycin , aminoglycosides , daptomycin , linezolid , and also β-lactams [126,127 ... how to scan picture to wordWebJun 17, 2024 · “High-dose” was considered to be ≥10 mg/kg daily and ≥9mg/kg daily, respectively. In both studies, the daptomycin MIC was 4 mg/L in ~ 70% of patients.3,4 … how to scan pokemon cards in pokemon goWebSep 4, 2024 · A case series of long-term high-dose daptomycin (mean dose 8 mg/kg TBW for at least 14 days) described 3 of 61 patients, 2 of whom … northmsaa.orgWeb110 Conventional daptomycin doses, based on actual body weight, result in sufficient 111 drug exposure to meet effective area under the curve (AUC) to minimum inhibitory 112 … how to scan pixmaWebDose based on total body weight for non-obese patients. For BMI > 30 use adjusted body weight. AdjBW= IBW + 0.4(TBW-IBW) VRE bacteremia/invasive VRE infections: ... - … how to scan pokemon cards