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WebFeb 6, 2024 · High SHBG Certain SHBG mutations that elevate SHBG are known to be negatively correlated with type 2 diabetes (T2DM), where high circulating SHBG can prevent the development of T2DM without altering insulin secretion, but instead via regulating fasting blood sugar. If your SHBG levels are too high, it likely means that less of your total testosterone is free testosterone that's available for your tissues to use. So, your tissues may not be getting enough testosterone. High levels of SHBG may be related to: Liver disease Hyperthyroidism Eating disorders In females, using estrogen in medicine, such as: can a microwave sit on top of a refrigerator
SHBG, sex hormone binding globulin levels, causes of high or low SHBG
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