WebBackground and objective: Atacicept is an inhibitor of the B lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL), and is being studied in relation to … Web20 apr. 2024 · ION-827359 is a 2·5-generation antisense oligonucleotide drug targeted to reduce the ENaC protein. This study evaluated the safety, pharmacokinetics (PK), and …
A Study to Assess the Safety, Tolerability, and Efficacy of ION …
WebFull Analysis Set (FAS) included all randomised subjects who received at least 1 dose of study drug (ION‑827359 or placebo) and who had at least 1 post-Baseline efficacy … Web29 mrt. 2024 · We Are Transforming the Standard of Care and Pioneering New Markets As the leader in RNA-targeted therapeutics for more than three decades, Ionis has focused … h\u0026m mens white sweatpants
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WebIntroduction Cystic fibrosis (CF) is a multisystem, life-threatening, autosomal recessive genetic disease resulting from mutations in the cystic fibrosis transmembrane … Web22 jun. 2024 · Drug: ION-827359 Drug: Placebo. Phase 2. Detailed Description: This was a multi-center, double-blind, placebo-controlled, randomized, Phase 2a study of ION … WebA Double-Blind, Placebo-Controlled, Dose-Escalation, Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple … h\u0026m meses sin intereses 2022