WebJul 18, 2024 · The anticholinergic actions of meclizine may also inhibit lactation. Renal impairment - There is limited data on how renal impairment affects the pharmacokinetics … WebAug 9, 2024 · Meclizine belongs to a class of drugs called antihistamines. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat …
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WebJan 16, 2024 · Meclizine (mek' li zeen) is a first generation antihistamine that belongs to the piperazine class of these agents (with cyclizine and hydroxyzine) which are used largely for their antiemetic and sedative … WebAug 12, 2015 · Meclizine is an attractive potential therapeutic agent for IRI, since it is well established to be safe in humans and it has an unusual mechanism of protection. … esther brini
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WebThe effect of renal impairment on the pharmacokinetics of meclizine has not been evaluated. Because of a potential for drug/metabolite accumulation, meclizine hydrochloride should be administered with caution in patients with renal impairment and in the elderly, as renal function generally declines with age. 8.8 Genetic CYP2D6 Polymorphism WebApr 1, 2024 · Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of meclizine in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving meclizine. … WebAntivert/Bonine/Meclizine Hydrochloride/Travel Sickness Oral Tab Chew: 25mg ... Specific guidelines for dosage adjustments in renal impairment are not available; however, drug and metabolite accumulation is possible in the presence of renal impairment; use caution. ... but also on bladder function, the eye, and temperature Additive sedation may ... esther brock bird