WebPhorbol 13-butanoate CAS Number: 100929-94-0: Molecular Weight: 434.52300: Density: N/A: Boiling Point: N/A: Molecular Formula: C 24 H 34 O 7: Melting Point: N/A: MSDS: N/A … WebPhorbol 12,13-dibutyrate (PDBu) is a phorbol ester which is one of the constituents of croton oil. As an activator of protein kinase C, it is a weak tumor promoter compared to 12-O …
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WebDec 27, 2012 · Interestingly, phorbol esters, similar to butyrate, exhibit differentiating potential involving activation of PKC . Phorbol esters such a phorbol-12-myristate-13- acetate (PMA) are useful experimental analogs of diacylglycerol, the physiological activator of PKC [27] also exhibiting the potential to activate MAPK [28] and, as a consequence, the ...
Webphorbol-diester hydrolase Alternative Name(s) diacylphorbate 12-hydrolase: Reaction catalysed; H2O + phorbol 12,13-dibutanoate => butanoate + H(+) + phorbol 13-butanoate: … WebThe effects of n-butyrate and 12-O-tetradecanoyl-phorbol-13-acetate (TPA) on both EBV-antigen induction and cell differentiation in two virus-nonproducer lymphoblastoid cell lines, Raji and NC37, were now studied. The following observations were made (1). On its own either drug induced 1–2 per cent of cells to EBV-early-antigen positivity in ...
WebMar 30, 2024 · We have previously found that the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) induces specific transcription of tRNA and 5S RNA genes in Drosophila Schneider S-2 cells (M. Garber, S. Panchanathan, R. F. Fan, and D. L. Johnson, J. Biol. Chem. 266:20598-20601, 1991). Having derived cellular extracts from TPA-treated cells, that are … WebWe studied the ability of inducers and inhibitors of erythroid differentiation of K562 leukemia cells, such as sodium butyrate, dimethyl sulfoxide, and phorbol-12-myristate-13-acetate, respectively, to modulate sensitivity of these cells to nonspecific lysis (nonrestricted with respect to antigens of the major histocompatibilty complex) mediated by natural human …
WebGene Ontology Term: phorbol-diester hydrolase activity GO ID GO:0050181 Aspect Molecular Function Description Catalysis of the reaction: H2O + phorbol 12,13-dibutanoate = …
WebAug 1, 2024 · Tiglilane diterpene group compounds such as phorbol-12-decanoate, phorbol-12,13,20-triacetate, 12-O-tetradecanoylphorbol-13-acetate, and others. Compounds of this type had been reported antivirals activities such as anti-HIV-1 and anti-HIV-2 ( Nothias-Scaglia et al., 2015; Olivon et al., 2015 ). novella fire in the holeWebSYMPTOMS: This material may cause skin irritation. ACUTE/CHRONIC HAZARDS: This compound may cause irritation upon contact with skin. (NTP, 1992) Reactivity Profile This material may be sensitive to prolonged exposure to air, light and ambient temperatures. It may also be subject to autooxidation. (NTP, 1992) novella hair salon crown pointWebPhorbol esters such a phorbol-12-myristate-13- acetate (PMA) are useful experimental analogs of diacylglycerol, the physiological activator of PKC [27] also exhibiting the potential to activate MAPK [28] and, as a consequence, the AP-1 response. novella grey backpackWebContact China Manufactory Shaanxi Dideu Medichem Co. Ltd for the product PHORBOL 13-BUTYRATE, 4BETA. Chat now for more business. novella hardwood floorsWebPhorbol 12,13-dibutyrate (PDB), a potent activator of protein kinase C … Polymyxin B, a selective inhibitor of protein kinase C, diminishes the release of noradrenaline and the enhancement of release caused by phorbol 12,13-butyrate Naunyn Schmiedebergs Arch Pharmacol. 1986 Oct;334(2):218-21. doi: 10.1007/BF00505825. ... how to sort y axis in tableauWebUsing BCBL-1 cells that harbour HHV-8 but lack Epstein-Barr virus, we demonstrate that sodium butyrate is much more effective than the phorbol ester 12-O-tetradecanoyl … novella hawthorneWebStructure, properties, spectra, suppliers and links for: 4β-Phorbol 12,13-dibutyrate, Phorbol 12,13-dibutyrate, 37558-16-0. Jump to main content Jump to site nav Home how to sort your outlook inbox by categories