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WebJun 20, 2024 · RELION (for REgularised LIkelihood OptimisatioN) is a stand-alone computer program for Maximum A Posteriori refinement of (multiple) 3D reconstructions or 2D class averages in cryo-electron microscopy. It is developed in the research group of Sjors Scheres at the MRC Laboratory of Molecular Biology. The underlying theory of MAP refinement is ... WebOct 20, 2024 · The cryo-electron microscopy (cryo-EM) is one of the most powerful technologies available today for structural biology. The RELION (Regularized Likelihood Optimization) implements a Bayesian algorithm for cryo-EM structure determination, which is one of the most widely used software in this field. Many researchers have devoted … WebNote. As the cryo-EM resolution revolution progresses, software protectionism is also on the rise. We are proud to distribute relion under a GPLv2 license. This means that anyone … patrina turner