Splet17. dec. 2024 · Autophagy is a conserved, multistep pathway that degrades and recycles dysfunctional organelles and macromolecules to maintain cellular homeostasis. Mammalian target of rapamycin (mTOR) and adenosine-monophosphate activated-protein kinase (AMPK) are major negative and positive regulators of autophagy, respectively. In … SpletMichelle A. Zhuang is an academic researcher from Brown University. The author has contributed to research in topic(s): Kidney & Renal fibrosis. The author has an hindex of 3, co-authored 3 publication(s) receiving 99 citation(s).
Targeting tyrosine kinase receptors as the treatment of renal …
SpletProfessor of Medicine in the Department of Medicine, Brown University Splet07. apr. 2024 · High fat diet could cause kidney injury, and the underlying mechanism remains incompletely understood. In this study, we investigated the role of Wnt signaling in this process. Mice were fed with high-fat diet in vivo, and podocytes were stimulated with palmitate in vitro. In mice fed with high-fat diet, renal function was impaired, … how to do a bank transfer on xero
Brown University - Open Access Journals
SpletConsiderable evidences have indicated that elevated uric acid (UA) was involved in renal tubular injury leading to hyperuricemic nephropathy (HN). Scutellarin is a biologically active flavonoid derived from the Chinese traditional herb Erigeron breviscapus Hand-Mazz, which has been widely used in the treatment of cardiovascular and cerebrovascular diseases. In … Splet28. sep. 2024 · BackgroundEmerging evidence revealed that gut microbial dysbiosis is implicated in the development of plasma cell dyscrasias and amyloid deposition diseases, but no data are available on the relationship between gut microbiota and immunoglobulin light chain (AL) amyloidosis.MethodsTo characterize the gut microbiota in patients with … how to do a bank draft